DESIGNING SUPERIOR THERAPIES THROUGH AI
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EpiVax Therapeutics uses a unique set of immunoinformatics tools developed over two decades to rapidly design custom therapies for cancer patients.
ANCER
The "Answer" To Cancer
Ancer is an end-to-end, automated neoantigen identification and personalized cancer vaccine design platform [1]. Ancer leverages EpiVax's EpiMatrix and JanusMatrix algorithms, state-of-the-art tools that have been externally validated in several prospective vaccine studies and that are broadly utilized worldwide by pharmaceutical and biotechnology companies [2,3].
JANUSMATRIX
In silico removal of inhibitory antigens
The JanusMatrix algorithm, included in the Ancer platform, is a key differentiator of our technology. JanusMatrix, named after Janus — the Roman god of duality, is used to identify putative epitopes which have the potential to cross-react with the human genome [4].
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In the case of vaccines, cross conservation between human epitopes and the antigenic epitopes may indicate that such a candidate utilizes immune camouflage, thereby evading the immune response and making for an ineffective vaccine.
